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@article{WOS:001728083400001,
title = {Graphene and amorphous carbon coatings for nitinol cardiovascular stents
by direct chemical vapor deposition: A comparative insight},
author = {Pei Rou Ng and Yixin Zhang and Tania Jim Jia Min and Xuan Liu and Mo Lin and Artemii S Ivanov and Konstantin G Nikolaev and Remi Mahfouz and Talah M Tayeb and Nada Qari and Guillermo C Bazan and Vitaly Sorokin and Kostya S Novoselov and Daria V. Andreeva},
doi = {10.1016/j.matdes.2026.115864},
times_cited = {0},
issn = {0264-1275},
year = {2026},
date = {2026-05-01},
journal = {MATERIALS & DESIGN},
volume = {265},
publisher = {ELSEVIER SCI LTD},
address = {125 London Wall, London, ENGLAND},
abstract = {Carbon-based coatings are promising for biomedical implants, including
vascular stents, but fabrication on metals often requires adhesion
interlayers or polymer-assisted transfer, increasing cost and
complexity. Here, we report a simple, ambient-pressure chemical vapor
deposition (CVD) process for the direct, interlayer-free growth of two
carbon coatings on nitinol (NiTi) stents: few-layer graphene (FLG/NiTi,
170 +/- 20 nm) and amorphous carbon (a-C/NiTi, 620 +/- 30 nm). Both
coatings significantly enhanced corrosion resistance, with protection
efficiencies of 83.78% for FLG/NiTi and 89.19% for a-C/NiTi. Vascular
cell assays revealed distinct and clinically relevant biological
responses. a-C/NiTi promoted vascular endothelial cell (VEC)
proliferation (+17.2% at 96 h relative to bare NiTi) while suppressing
vascular smooth muscle cell (VSMC) proliferation (-25%), a desirable
outcome as excessive VSMC growth drives in-stent restenosis, whereas
endothelialization supports vessel healing. In contrast, FLG/NiTi
inhibited proliferation of both cell types (>50% reduction for VECs).
All samples exhibited excellent hemocompatibility (hemolysis < 0.2%),
and a-C/NiTi reduced platelet surface coverage by 30% compared with
bare NiTi, beneficial for mitigating thrombosis. Inflammatory assessment
further showed a 73% reduction in TNF-alpha secretion on a-C/NiTi in
comparison to bare NiTi. Together, these results demonstrate an
interlayer/ polymer-free route to carbon-coated NiTi stents with tunable
biological performance.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}

@article{WOS:001703236200001,
title = {Conjugated Oligoelectrolytes as Optical Probes},
author = {Samuel J W Chan and Ji-Yu Zhu and Guillermo C Bazan},
doi = {10.1021/acs.accounts.6c00017},
times_cited = {0},
issn = {0001-4842},
year = {2026},
date = {2026-04-01},
journal = {ACCOUNTS OF CHEMICAL RESEARCH},
volume = {59},
number = {7},
pages = {1202-1214},
publisher = {AMER CHEMICAL SOC},
address = {1155 16TH ST, NW, WASHINGTON, DC 20036 USA},
abstract = {Optical probes are essential tools for interrogating biological and
chemical systems invisible to the naked eye, providing insights into
molecular interactions, protein activity, and cellular trafficking.
Conjugated oligoelectrolytes (COEs), an emerging class of optical
probes, are synthetic organic amphiphiles defined by a pi-conjugated
backbone and charged pendant groups. COEs with a linear conjugated
structure and charged groups at the two termini can be designed to mimic
the molecular dimensions and arrangements of hydrophobic and hydrophilic
groups characteristic of lipid bilayers. This design drives their
spontaneous intercalation into and prolonged residence within biological
lipid bilayer membranes. By tailoring their molecular building blocks,
their electronic and photophysical properties as well as their
interactions with cells can be readily tuned, positioning COEs as a
versatile platform for developing molecular probes for fundamental
research and applied bioimaging across a range of biological systems.In
this Account, we describe the design strategies elaborated by our group
for developing COEs as optical probes, with a focus on their
applications and uses in elucidation and tracking of cellular membrane
properties. We show that COEs can be used to detect and visualize lipid
membranes at multiple length scales, ranging from single microbial cells
and exogenously isolated small extracellular vesicles and particles to
subcellular organelles and whole cells in live animal models. COEs also
function as effective nonlinear optical probes that are applicable in
advanced imaging modalities such as two-photon microscopy and stimulated
emission depletion microscopy to extract spatiotemporal information at
high resolution.We also provide our insights into how COEs can be
designed to be functional probes that exhibit predictable photophysical
behavior in response to the local molecular and chemical environment.
Using fluorescence lifetime imaging microscopy, the time-resolved
emission of COEs can be leveraged to provide insight into dynamic
processes such as rapid changes in membrane tension and long-term
changes in membrane rigidity and composition. We additionally elaborate
strategies for modulating interactions with biological membranes,
designing membrane-specific probes that respond to specific cellular
biophysical parameters, and offer perspectives and opportunities toward
developing a new platform for disease detection and diagnosis.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}

@article{WOS:001751918400001,
title = {Single-particle imaging uncovers reverse electron transfer efficiency
between Shewanella oneidensis MR-1 and shaped haematite},
author = {Yong Liu and Wentao Song and Weidong Zhang and Yuanmei Liang and Mukesh Saini and Yuanzhi He and Jing Zhu and Zhongxin Chen and Guoliang Zhang and Jin Xie and Xiaozhi Xu and Guillermo C Bazan and Jee Loon Foo and Matthew Wook Chang and Bin Liu and Xianwen Mao},
doi = {10.1038/s41929-026-01530-x},
times_cited = {0},
issn = {2520-1158},
year = {2026},
date = {2026-04-01},
journal = {NATURE CATALYSIS},
publisher = {NATURE PORTFOLIO},
address = {HEIDELBERGER PLATZ 3, BERLIN, 14197, GERMANY},
abstract = {Microbe-semiconductor hybrids hold promise for solar-to-chemical
conversion, but facet-dependent interfacial charge transfer remains
poorly understood due to structural heterogeneity and biological
complexity. Here we leverage a multimodal optical imaging platform to
probe the charge-transfer efficiency between Shewanella oneidensis MR-1
and 110/001-faceted haematite, at single-particle and
single-cell levels, in vivo and operando. We quantify the reverse
extracellular electron-transfer capabilities of Shewanella oneidensis
MR-1 via non-H2-mediated pathways, and identify that haematite's 110
facets synergistically exhibit stronger cell-binding ability and higher
charge-transfer efficiency. Furthermore, we discover that moderate cell
densities are key to enhancing per-cell electron injection, highlighting
the trade-off between total loading and individual cell efficiency, and
offering critical insights into biofilm structure optimization. Our
imaging tools and analytical framework may potentially extend to diverse
microbe-semiconductor hybrid systems, quantifying microscopic structural
and functional descriptors that enhance the fundamental understanding of
complex interfacial charge transfer, and inform rational biohybrid
design across applications.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}

@article{WOS:001666014800001,
title = {Spontaneously N-Doped Conjugated Polyelectrolyte Coatings Accelerate
Electron Uptake in Shewanella Oneidensis},
author = {Zhongxin Chen and Yilu Song and Samantha R McCuskey and Jianan Cai and Weidong Zhang and Nansi Zhou and David Ohayon and Fernando Lopez-Garcia and Alexey I Berdyugin and Xianwen Mao and Guillermo C Bazan},
doi = {10.1002/adma.202521386},
times_cited = {0},
issn = {0935-9648},
year = {2026},
date = {2026-02-01},
journal = {ADVANCED MATERIALS},
volume = {38},
number = {12},
publisher = {WILEY-V C H VERLAG GMBH},
address = {POSTFACH 101161, 69451 WEINHEIM, GERMANY},
abstract = {Bioelectrochemical systems interconvert electrical and chemical energy
using living microorganisms, but their efficiency remains limited by
slow electron exchange across abiotic-biotic interfaces. Herein, a
spontaneous n-doped water-dispersible conjugated polyelectrolyte (CPE),
PNB, is developed. The CPE self-assembles on the surface of Shewanella
oneidensis MR-1 to create biocompatible coatings that accelerate inward
extracellular electron transfer. PNB is obtained via an aldol
condensation reaction and is described by an acceptor-acceptor
pi-conjugated backbone bearing quaternary ammonium side chains. This
molecular architecture enables stable n-doping in aqueous media and a
broad reduction potential window. When integrated as a cathodic
interlayer, PNB-S. oneidensis biohybrids exhibit a 14-fold enhancement
in electron injection and a 4-fold increase in electro-driven succinate
production, compared to unmodified cells. Single-cell electrochemical
mapping confirms faster, more efficient per-cell electron influx. These
findings demonstrate that n-type CPEs can bridge external electrodes
with cellular metabolisms, opening a material-based route to
high-performance bioelectronic and electrosynthetic systems. By enabling
more facile charge transfer between synthetic semiconductors and living
catalysts, this work establishes a soft materials-driven framework for
designing electronically coupled microbial systems with potential to
advance sustainable bioelectronic technologies.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}

@article{WOS:001611972700001,
title = {Recent Advances of Conjugated Polymers-Based Biohybrid Systems for the
Synthesis of Value-Added Chemicals},
author = {Wen Yu and Shengpeng Xia and Miaomiao Zhang and Zhiqiang Gao and Fengting Lv and Yiming Huang and Haotian Bai and Guillermo C Bazan and Shu Wang},
doi = {10.31635/ccschem.025.202506431},
times_cited = {3},
year = {2026},
date = {2026-01-01},
journal = {CCS CHEMISTRY},
volume = {8},
number = {1},
publisher = {CHINESE CHEMICAL SOC},
address = {C/O DEPT INT AFFAIRS, SECRETARY OF CHEM SOC, PO BOX 2709, BEIJING
100080, PEOPLES R CHINA},
abstract = {Conjugated polymers (CPs) have garnered considerable attention for
biohybrid systems due to their intrinsic biocompatibility, superior
light-harvesting and charge-separation capabilities, and tunable
bioconductivity. This review outlines recent breakthroughs and emerging
paradigms in CP-based biohybrid systems, specifically in the field of
biosynthesis, which harness optical and electrical energy to generate
chemical energy. We begin by surveying photosynthetic biohybrid system
constructs that couple CPs with living microorganisms. In these systems,
CPs generate photoactive electrons as ``light-trapping antennas'' to
drive microbial synthetic pathways. Such platforms empower
microorganisms to valorize CO2, N-2, and other simple substrates into
renewable energy fuels and chemicals by utilizing light energy. Beyond
solar-driven processes, electrosynthesis biohybrids offer an orthogonal
yet equally sustainable strategy by leveraging renewable electricity. In
electro-synthetic biohybrid systems, CPs act as electronic bridges that
interface with electroactive microorganisms, significantly enhancing the
interfacial electron transfer rate at the material-biological interface
and thus boosting the efficiency of electricity-chemical conversion. In
summary, these advances not only expand the functional repertoire of
CP-based biohybrid systems but also inform rational design principles
aimed at realizing scalable, sustainable, and programmable biosynthetic
platforms ideas to promote their industrial synthesis of chemicals
powered by solar and electrical inputs.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}